Large-scale genetic study provides new insight into the causes of migraine
The results of the largest genetic study on migraine thus far were published online in the journal Nature Genetics today, June 20. The study was based on DNA samples of 375,000 European, American and Australian participants. Almost 60,000 of them suffer from migraine. The researchers combined data from 22 genome-wide association studies including new data from around 35,000 migraine sufferers. From the millions of genetic variants analyzed, 38 independent genomic regions were shown to be associated with migraine . Only ten of these regions have been implicated in migraine susceptibility before. The study was conducted by members of the International Headache Genetics Consortium including migraine research groups from Australia, Denmark, Estonia, Finland, Germany, Iceland, the Netherlands, Norway, Spain, Sweden, the UK and USA. "Our consortium is devoted to uncovering the genetic causes of migraine and during the past few years we have been able to identify many risk ...